# Install EPEL if you haven't already.
% yum install http://dl.fedoraproject.org/pub/epel/6/i386/epel-release-6-8.noarch.rpm

# Download the RPM here
% wget http://www.bromosapien.net:8080/others/skype-4.2.0.11-4.el6.i686.rpm

# Install it as so
% yum install skype-4.2.0.11-4.el6.i686.rpm

# If you receive an error about a GPG key, you may import my key as necessary.
% wget http://www.bromosapien.net:8080/others/SYRKIT-GPG-KEY.pub
% rpm --import SYRKIT-GPG-KEY.pub

자료출처: http://community.skype.com/t5/Linux/CentOS-RHEL-6-Skype-4-2-RPM-Installation-Steps/td-p/1740485